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Viagra:
Viagra (Sildenafil Citrate) is a prescribed drug used for treatment of erectile dysfunction at males. Its other name is Sildenafil Citrate used as selective inhibitor and slows down the cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) which causes the decline of cGMP in the coupus cavernosum (penis).
Adverse Event |
Percentage of Patients |
Reporting Event |
|
|
VIAGRA N=734 |
PLACEBO N=725 |
| Headache |
16% |
4% |
| Flushing |
10% |
1% |
| Dyspepsia |
7% |
2% |
| Nasal Congestion |
4% |
2% |
| Urinary Tract Infection |
3% |
2% |
| Abnormal Vision |
3% |
0% |
| Diarrhea |
3% |
1% |
| Dizziness |
2% |
1% |
| Rash |
2% |
1% |
Apart from the above, Viagra® has also shown interactions with many other drugs.
Be careful to use Viagra with other drugs as Sildenafil is often affected with harmful after-effects. For safety reason, consult your doctor about taking Viagra with any of the following prescribed or over-the-counter drugs:
* nitrate drugs for angina or heart problems (nitroglycerin (Nitrostat, Nitrolingual, Nitro-Dur, Nitro-Bid, Minitran, Deponit, Transderm-Nitro), isosorbide dinitrate (Dilatrate-SR, Isordil, Sorbitrate), and isosorbide mononitrate (Imdur, ISMO, Monoket), amyl nitrate;
* HIV medicines ( amprenavir (Agenerase), tipranavir (Aptivus), darunavir (Prezista), efavirenz (Sustiva), nevirapine (Viramune), indinavir (Crixivan), saquinavir (Invirase, Fortovase), lopinavir/ ritonavir (Kaletra), fosamprenavir (Lexiva), ritonavir (Norvir), atazanavir (Reyataz), or nelfinavir (Viracept);
* antifungal medications( itraconazole (Sporanox) or ketoconazole (Nizoral);
* antibiotics (erythromycin (E-Mycin, Eryc, Ery-Tab) or clarithromycin (Biaxin), doxazosin (Cardura), prazosin (Minipress), Terazosin (Hytrin);
* bosentan (Tracleer), cimetidine (Tagamet, Tagamet HB);
* carbamazepine (Tegretol), phenobarbital (Luminal), or phenytoin (Dilantin);
* Rifampin (Rifadin, Rimactane) or rifabutin (Mycobutin).
Cialis:
Cialis(tadalafil) is another selective inhibitor intended for adjustment cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Its second name is Tadalafil useful for therapy of impotence or erectile dysfunction(ED).
Like Viagra, Cialis too has an enormous list of side effects as listed below:
| |
Placebo |
Tadalafil 5 mg |
Tadalafil 10 mg |
Tadalafil 20 mg |
| Adverse Event |
(N=476) |
(N=151) |
(N=394) |
(N=635) |
| Headache |
5% |
11% |
11% |
15% |
| Dyspepsia |
1% |
4% |
8% |
10% |
| Back Pain |
3% |
3% |
5% |
6% |
| Myalgia |
1% |
1% |
4% |
3% |
| Nasal congestion |
1% |
2% |
3% |
3% |
| Flushing* |
1% |
2% |
3% |
3% |
| Pain in limb |
1% |
1% |
3% |
3% |
Drug interaction of Cialis is the same as Viagra has.
Have a talk with your doctor to find out what drugs are suitable to use with Cialis for you personaly.
First of all, Cialis is extremely forbidden to take with alpha blockers (Nitrates), HIV medicines ( amprenavir (Agenerase), tipranavir (Aptivus), darunavir (Prezista), efavirenz (Sustiva), nevirapine (Viramune), indinavir (Crixivan), saquinavir (Invirase, Fortovase), lopinavir/ritonavir (Kaletra), fosamprenavir (Lexiva), ritonavir (Norvir), atazanavir (Reyataz), or nelfinavir (Viracept); itraconazole (Sporanox) or ketoconazole (Nizoral); carbamazepine (Tegretol), phenobarbital (Luminal), or phenytoin (Dilantin) or rifampin (Rifadin, Rimactane); cimetidine (Tagamet, Tagamet HB); doxazosin (Cardura), prazosin (Minipress), terazosin (Hytrin); erythromycin (E-Mycin, Eryc, Ery-Tab) or clarithromycin (Biaxin).
*Source, drugs.com
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